Medical Journal of The Islamic Republic of Iran (MJIRI)
Iran University of Medical Sciences
Thu, Dec 12, 2024
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Volume 10, Issue 1 (5-1996)
Med J Islam Repub Iran 1996 |
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AFSHARYPOUR S, SHAFII K, AKBARY M E, ZARGARZADEH M R. PREPARATION AN D CLINICAL EVALUATION OF SOME ANTI-ANORECTAL DISEASE DRUGS OBTAINED FROM MEDICINAL PLANTS. Med J Islam Repub Iran 1996; 10 (1) :73-77
URL: http://mjiri.iums.ac.ir/article-1-1224-en.html
URL: http://mjiri.iums.ac.ir/article-1-1224-en.html
From the Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan
Abstract: (3509 Views)
The hydroalcoholic extracts of dried ligulate florets of Calendula officinalis
L., dried leaves of Plantago major L., and dried aerial parts of Vinca major L. were
prepared and used as the main active ingredients of two types of anti-anorectal
disease ointments and suppositories. Benzocaine was used in one of the
formulations, while a mixture of belladonna dry extract and ephedrine sulfate was
used in the other. The effects of both prepared formulations were investigated in
patients suffering from anorectal diseases, using relevant placebos for
comparison.
The results indicated that the prepared drugs were significantly effective in the
treatment of anorectal diseases. Formulations containing benzocaine proved to be
more effective in patients suffering from hemorrhoids, while formulations containing
belladonna dry extract and ephedrine sulfate were more effective in anal
fissure and proctitis.
Type of Study: Original Research: Basic Science in Medicine |
Subject:
Pharmacology
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