From the Department of Obstetrics and Gynecology, Shahid Rahnamun Hospital, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran
Abstract: (4680 Views)
We treated ten men and ten women suffering from hypogonadotropic
hypogonadism with LHRH. Our method of treatment differed 'from others
in that a mini pump was not available at the onset of the study. Nine women
were given injections via a heparinized indwelling catheter every 120 minutes
for 14 days, i,e. the proliferative phase. After ovulation, 3000 IU human
chorionic gonadotropin (HCG) was administered every two days. A minipump
was used for only one patient. From among these nine female patients,
three pregnancies occurred, In male subjects, 50-100 micrograms LHRH
was subcutaneously self-administered twice daily, and 5000 IU HCG was
given intramuscularly twice weekly. With this treatment, secondary sexual
characteristics appeared after a few months, including nocturnal ejaculation,
growth of testes, and elevation of serum testosterone levels.