Volume 9, Issue 3 (10-1995)                   Med J Islam Repub Iran 1995 | Back to browse issues page

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KUCHARZ E J. BINDING OF NAPROXEN TO SERUM PROTEINS IN PATIENTS WITH LIVER CIRRHOSIS AND HEALTHY INDIVIDUALS. Med J Islam Repub Iran 1995; 9 (3) :217-219
URL: http://mjiri.iums.ac.ir/article-1-1321-en.html
BINDING OF NAPROXEN TO SERUM PROTEINS IN PATIENTS WITH LIVER CIRRHOSIS AND HEALTHY INDIVIDUALS
EUGENE J KUCHARZ
From the Fourth Department of Internal Medicine, Silesian University School of medicine, ul. Edukacji 102, pl 43- 100 Tychy, Poland.
Abstract:   (3886 Views)
A three-fold decrease of the in vitro ability of serum proteins to bind naproxen was shown in patients with cirrhosis of the liver compared to healthy individuals. This decrease was caused by quantitative changes in serum proteins in the sera of patients with liver damage. Lower doses of naproxen are therefore suggested in the treatment of patients with liver dysfunction.
Keywords: Naproxen, Liver, cirrhosis, Serum proteins.
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Type of Study: Original Research | Subject: Internal Medicine
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