From the Department of Toxicology and Pharmacology, Tehran University of Medical Sciences
Abstract: (4055 Views)
Organophosphate chronic toxicity has been evaluated in this study. Biological
screening for organophosphate insecticide-exposed workers is mostly recommended
for mixers, loaders, formulators and spraymen. We have studied 17 occupationally
exposed persons to pesticides. Using Ellman's colorimetric method, their plasma
cholinesterase activities have been measured. Results show that the appearance of
some of the symptoms of chronic organophosphate toxicity depends on the extent
of plasma cholinesterase activity reduction. Our results also indicate that headache,
weakness, nervousness, memory difficulty, tremors, insomnia and dizziness areā¢
the main problems demonstrated in these workers.