MOSHTAGHIE A, SANDUGHCHIN M, BADIL A, AZANI M. DEVELOPMENT OF A METHOD FOR ALUMINIUM DETERMINATION IN SERUM AND DIALYSIS FLUID BY FLAMELESS ATOMIC ABSORPTION WITH GRAPHITE FURNACE. Med J Islam Repub Iran 1995; 9 (3) :233-237
URL:
http://mjiri.iums.ac.ir/article-1-1324-en.html
From the Department of Biochemistry, School of Pharmacy Isfahan University of Medical Sciences, Isfahan
Abstract: (4384 Views)
Aluminium determination was carried out in serum and dialysis fluid by a
simple and reliable method of nameless atomic absorption with graphite furnace . .
No preparatory procedures are required for water and dialysis fluid. In this method
serum was mixed with 0.2% HNO, to allow complete combustion of the samples
in order to improve analytical precision. The method has a sensitivity of 15 pg and
detection limit of 2.1 µg AI/L.
The aluminium contents of the main water supply, be-distilled water and
dialysis fluid were 52, I, and 44 µg/L respectively. The mean value for normal
serum aluminium in Isfahan was 3.6 µg/L. Serum aluminium concentration in
chronic renal failure was measured in pre- and post-dialysis samples. The mean
values for the serum aluminium levels pre- and post-dialysis were 30.5 and 71.08
µg/L with a range of 9-60 and 21-123 µg/L, respectively. Pre- and post-dialysis
serum aluminium values in female patients were within the range of 1-42 and 12-
66 µg/L with mean values of 18.25 and 40.5 µg/L, respectively. Instrumental
settings and sample handling are discussed.