From the Department of Community Health
Abstract: (5661 Views)
The study was conducted to determine the prevalence of goiter and
hypothyroidism in two groups of the population at various stages of social development
and to determine its association with malnutrition and dietary intake. Aboriginal
inhabitants (Orang Asli), a resettlement rural village (Betau Post), a traditional
village in the jungle (Lanai Post) and a modern village settlement near Kuala Lumpur
City (Bukit Lanjan) were selected. Three Malay villages with almost similar
environments were selected for comparison. The study included house to house
interviews, anthropometric, clinical and biochemical assessment of 1419 samples
and estimation of iodine concentration in the drinking water of the areas studied. The
World Health Organization criteria for classification of goiter were used. It was
found that all Orang Asli settlements in rural areas were iodine deficient. The
prevalence of goiter and hypothyroidism were higher among Orang Asli at all ages
compared to Malays, and increased with remoteness of the areas (20-70% and 20-
30% respectively). Apart from iodine deficiency, a high intake of cassava and
deficient intake of sea foods and protein diets were also significantly related with
high prevalence of goiter. Among children, goiter was associated with the level of
thyroid stimulating hormone (TSH) whereas among adults, body mass index (BM!),
triiodothyronine and thyroxine levels were predictors for the presence of goiter. In
conclusion, goiter and hypothyroidism were more common among Orang Asli
compared to Malays, and were associated with rural location and poverty.