From the Department of Pathology. Tile Cancer Institute, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Abstract: (3851 Views)
Peripheral neuroepitbelioma (PN) is a rare highly malignant tumor, classified
in the group of small round cell tumors. We report eight cases of PN, based on
histologic appearance and immunohistochemical staining for neuron-specific enolase
(NSE). Electron microscopy was also performed in three cases.
The tumors exhibited rapid local growth, leading to limb amputation in five
cases. Histologically the presence of Homer-Wright rosettes is a characteristic of this
neoplasm. Tumoral cells are generally positive for NSE. The relationship ofPN with
Ewing's sarcoma is discussed.
Type of Study:
Original Research |
Subject:
Pathology