From the Institute of Biochemistry and Biophysics, University of Tehran, Islamic Republic of Iran.
Abstract: (3807 Views)
In this study the nature of chromosomal proteins, his tones and nonhistone
in resident alveolar macrophages was investigated in comparison to
peritoneal neutrophils and calf thymus proteins. Cells were obtained by
lavaging the lung and after purity determination they were subjected to
fractional extraction procedures. Proteins were then analysed on SDS
polyacrylamide gels and densitometric scans were obtained. The results
show that in macrophages, the pattern of histone and nonhistone proteins
were similar to thymus proteins, two distinct and specific proteins HIĀ° and
HMGI4b and also a protein with a molecular weight of I2kd (Hx) were
present. These data suggest a different chromatin protein pattern in
pulmonary alveolar macrophages.