Volume 3, Issue 1 And 2 (8-1989)                   Med J Islam Repub Iran 1989 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
GOLIAEI B, RABBANI A. THE ROLE OF ALVEOLAR MACROPHAGES IN THE PRODUCTION OF COLONY –STIMULATING FACTOR BY THE LUNG. Med J Islam Repub Iran 1989; 3 (1 and 2) :51-56
URL: http://mjiri.iums.ac.ir/article-1-1600-en.html
THE ROLE OF ALVEOLAR MACROPHAGES IN THE PRODUCTION OF COLONY –STIMULATING FACTOR BY THE LUNG
B GOLIAEI , A RABBANI
From the Institute of Biochemistry and Biophysics, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Abstract:   (4216 Views)
The role of alveolar macrophages in the production of granulocyte/ macrophage colony-stimulating factor(s) by the rat lung was investigated. Lavaged lungs, when incubated at proper weight per volume of culture medium, produced the same amount of colony-stimulating factor as unlavaged ones. Both lavaged and unlavaged lungs produced similar types of colony-stimulating factor (s). Prolonged incubation of lavaged and unlavaged lung tissues did not result in higher levels of activity beyond that produced by 48 hrs of incubation. Alveolar macrophages recovered from the lung did not produce colony-stimulating factors when they were cultured unstimulated and under similar conditions as lung conditioned medium. The results indicated that alveolar macrophages did not play a significant role in colony stimulating factor (s) production by the lungs and when unstimulated, they did not produce colony-stimulating factors directly.
Full-Text [PDF 420 kb]   (1594 Downloads)    
Type of Study: Original Research: Basic Science in Medicine | Subject: Medical Basic Sciences
Add your comments about this article : Your username or Email:
CAPTCHA
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.