Volume 3, Issue 1 And 2 (8-1989)                   Med J Islam Repub Iran 1989 | Back to browse issues page

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RAFIEI S, MOSAFA N. ANTI-ENDOTHELIAL CELL ANTIBODIES AND CIRCULATING IMMUNE COMPLEXES, A POSSIBLE PROGNOSTIC TOOL IN IDDM ANGIOPATHY. Med J Islam Repub Iran 1989; 3 (1 and 2) :69-74
URL: http://mjiri.iums.ac.ir/article-1-1603-en.html
ANTI-ENDOTHELIAL CELL ANTIBODIES AND CIRCULATING IMMUNE COMPLEXES, A POSSIBLE PROGNOSTIC TOOL IN IDDM ANGIOPATHY
S RAFIEI , N MOSAFA
From the Department of Immunology and Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Abstract:   (4283 Views)
52 patients suffering from ID D M (insulin-dependent diabetes mellitus) were studied for anti-endothelial cell antibodies (AEA) and circulating immune complexes (CIC). 20 had a high CI C level, and eight demonstrated AEA, of whom five had retinopathy and three did not show any obvious vascular complication. It has been shown that C3, C4 and CH50 levels were also decreased. AEA were evaluated by indirect immunoflourescent technique, using rat pancreas tissue as the antigen. To estimate the CIC level, PEG precipitating method was used. It was suggested that bydemonstratingAEJ', we will be able 􀀽o evaluate the prognosis ofIDDM, especially the long standing phase, with no vascular complication.
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Type of Study: Original Research: Basic Science in Medicine | Subject: Immunology
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