Background: To investigate thyroid
function in preeclamptic patients in comparison with normal pregnant women.
Methods: In this analytical
cross-sectional study free Thyroxine (T4), and Thyroid Stimulating Hormone (TSH)
levels were measured in 100 preeclamptic patients and were compared with Free
T4 and TSH levels in 101 normal pregnant women in their third trimester of
pregnancy. Patients with thyroid or other systemic disorders were excluded from
this study.
Results: A significant difference in
concentration of free T4 levels (0.729 ±0.324 ng/ dl versus 0.929± 0.314 ng/dl,
p <0.001) was observed in the preeclamptic group compared with the
normotensive group, but the mean TSH level was not significantly different
(2.935±1.16 mIU/L versus 2.339±1/15 mIU/L, p = 0.170).
Conclusion: Women who develop
preeclampsia are more likely to have lower normal limits of thyroid function during
their final weeks of pregnancy.
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