Volume 28, Issue 1 (1-2014)                   Med J Islam Repub Iran 2014 | Back to browse issues page

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Khalesi N, Khosravi N, Rezaee M R, Amini L. Prevalence of microcytosis in neonates: a cross-sectional study in Tehran. Med J Islam Repub Iran 2014; 28 (1) :804-807
URL: http://mjiri.iums.ac.ir/article-1-2517-en.html
Prevalence of microcytosis in neonates: a cross-sectional study in Tehran
Nasrin Khalesi , Nastaran Khosravi , Mohammad Reza Rezaee , Leila Amini
Midwifery Department, Faculty of Nursing & Midwifery, Iran University of Medical Sciences, Tehran, Iran. , amini.l@iums.ac.ir
Abstract:   (3685 Views)

  Background :Identification of α thalassemia (α thal) a common cause of microcytosis during neonatal periods is an important step prevent unnecessary interventions. Thus, low the mean corpuscular volume (MCV) and the mean corpuscular hemoglobin (MCH) may consider as α-thalassemia key detection points. The present study aimed to determine the prevalence of microcytosis among neonates who born in Tehran, Iran.

  Methods : Cord blood samples were collected from 1001 newborns after birth in labor room and their red blood cell parameters were investigated.

  Results : MCV was 114.2 fl (95% CI: 113.5-114.9) and twenty three neonates (2.3%) had MCV less than 94 fL that classified as microcytosis and 4 (0.40%) had both low MCH and MCV.

  Conclusion : Low MCV especially in normal Hb newborns may hints for α thal detection.

Keywords: Thalassemia, mean corpuscular hemoglobin, microcytosis, HbBarts.
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Type of Study: Original Research | Subject: Pediatric
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