Volume 29, Issue 1 (1-2015)                   Med J Islam Repub Iran 2015 | Back to browse issues page

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Zamani M, Movahhedi M, Nourbakhsh S M, Ganji F, Rafieian-Kopaei M, Mobasheri M, et al . Therapeutic effects of Ventolin versus hypertonic saline 3% for acute bronchiolitis in children. Med J Islam Repub Iran 2015; 29 (1) :428-432
URL: http://mjiri.iums.ac.ir/article-1-2888-en.html
Shahrekord University of Medical Sciences, Shahrekord, Iran. , keivaniz@yahoo.com
Abstract:   (4241 Views)

  Background: Complications of Ventolin as the most common drug used for bronchiolitis are widely known. The present study was conducted to determine the efficacy of hypertonic saline 3%, compared with Ventolin, for treatment of acute bronchiolitis in children.

  Methods : This double-blinded clinical trial study was conducted in Hajar Hospital, Shahrekord, Iran, from 2011 to 2012. A total of 70 patients under the age of two years with bronchiolitis were divided into two groups of 35 each. Ventolin nebulizer and hypertonic saline 3% nebulizer three times per day were administered in the first (Ventolin) and second (Hypersaline) group, respectively. The length of recovery was compared between the two groups. The data were analyzed by SPSS software (version 22) using chi-square, t-test, paired t-test, and Mann-Whitney.

  Results : The mean±SD length of recovery was 4.14±0.9 and 3.06±0.6 in the Ventolin and hypersaline groups, respectively. The mean duration of recovery was significantly lower in the hypersaline group (p<0.001).

  Conclusion : Hypertonic saline 3% nebulizer has more pleasant therapeutic effects on acute bronchiolitis than Ventolin. Therefore, use of hypertonic saline 3% nebulizer is recommended for the treatment of acute bronchiolitis in children under two years old.

Full-Text [PDF 330 kb]   (1872 Downloads)    
Type of Study: Original Research | Subject: Pediatric

Podcast [MP3 6373 KB]  (349 Download)
Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.