Volume 20, Issue 2 (7-2006)                   Med J Islam Repub Iran 2006 | Back to browse issues page

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BASSIRI JAHROMI S, ABACHI M, KHAKSAR A A. DETECTION OF CRYPTOCOCCUS NEOFORMANS BY SEMINESTED PCR IN CEREBROSPINAL FLUID. Med J Islam Repub Iran 2006; 20 (2) :62-65
URL: http://mjiri.iums.ac.ir/article-1-361-en.html
DETECTION OF CRYPTOCOCCUS NEOFORMANS BY SEMINESTED PCR IN CEREBROSPINAL FLUID
SHAHINDOKHT BASSIRI JAHROMI , MANSOOR ABACHI , ALI ASGHAR KHAKSAR
Abstract:   (4852 Views)

 ABSTRACT

 Life-threatening infections caused by the encapsulated fungal pathogen Cryptococcus neoformans have been increasing steadily over the past 10 years. Cryptococcus neoformans is recognized as the most frequent fungal infection of the central nervous system (CNS) in immunocompetent as well as immunocompromised patients. We report the development of a semi-nested- PCR-based assay for the detection of C. neoformans in less than 100 yeast cells per ml of cerebrospinal fluid (CSF).

Keywords: Cryptococcus neoformans, PCR, Semi-nested PCR, CSF
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Type of Study: Original Research | Subject: Medical Mycology and Biotechnology
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