Volume 19, Issue 4 (2-2006)                   Med J Islam Repub Iran 2006 | Back to browse issues page

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AHMADI F, LESSAN-PEZESHKI M, KHATAMI M, MAHDAVI-MAZDEH M, MAZIAR S, SEIFI S. BENEFICIAL EFFECT OF LOW DOSE CYCLOSPORINE WITH MMF (MYCOPHENOLATE MOFETIL) IN RENAL ALLOGRAFT RECIPIENTS. Med J Islam Repub Iran 2006; 19 (4) :329-332
URL: http://mjiri.iums.ac.ir/article-1-559-en.html
BENEFICIAL EFFECT OF LOW DOSE CYCLOSPORINE WITH MMF (MYCOPHENOLATE MOFETIL) IN RENAL ALLOGRAFT RECIPIENTS
F AHMADI , M LESSAN-PEZESHKI , M.R KHATAMI , M MAHDAVI-MAZDEH , S MAZIAR , S SEIFI
Department of Nephrology, Tehran University of Medical Sciences, Imam Khomeini Hospital , f_ahmadish@yahoo.com
Abstract:   (5055 Views)
Background: Calcineurin inhibitors (CNI) have significantly reduced the incidence of acute rejection. Nephrotoxicity however may contribute to long-term allograft dysfunction. Mycophenolate mofetil (MMF) may allow cyclosporine (CsA) dose reduction without increasing the risk of rejection. Methods: In seventy-eight living unrelated kidney transplant patients with renal dysfunction, we studied the effect of CsA dose reduction in association with MMF on renal function and cardiovascular risk profile. Results: We reduced the cyclosporine dose from mean 3.5±0.94 mg/kg/d to 2±0.51 mg/kg/d,p
Keywords: Cyclosporine-Mycophenolate Mofetil-Graft survival-Chronic Nephropathy- Hyperlipidemia
Full-Text [PDF 235 kb]   (1355 Downloads)    
Type of Study: Original Research: Clinical Science | Subject: Nephrology
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