NOORBAKHSH S, ASHTIANI F, RIMAZ S, BAKHSHAYESH M. MUMPS MENINGOENCEPHALITIS IN PEDIATRIC WARD OFRASOOLAKRAMHOSPITAL IN TEHRAN, IRAN, 1999-2000. Med J Islam Repub Iran 2004; 18 (2) :123-126
URL:
http://mjiri.iums.ac.ir/article-1-629-en.html
From the Department of Pediatrics. Rasool Akram Hospital. Iran University of Medical Sciences,. Tehran,l.R.lran. , saminoor@hbi.dmr.or.ir
Abstract: (4821 Views)
To determine the frequency of mumps infection in children hospitalized with aseptic
meningoencephalitis ( ME), as well as its correlation with parotiditis, this case-series
study was conducted in the pediatric ward ofRasool Akram Hospital in Tehran, Iran,
from 1 999 to 2001.
T he blood samples of these patients were tested for specific IgM antibody for
mumps by Elisa method. The results of this study showed that 62.7% of children with
ME were IgM positive, and the remaining (37.3%) were IgM negative. There was a
significant correlation between positive IgM and the presence of parotiditis. However,
no correlation was noted between age, sex and season with IGM positivity except for
CSF changes (aseptic meningitis) between the two groups. It can be concluded that the
presence of neural symptoms (especially aseptic meningitis) in children less than 7 years
of age with parotiditis could indicate mumps ME, especially in the spring. Due to a
higher percentage of unvaccinated young persons « 15yr old) in Iran, probably the
incidence rate of mumps infection and its sequelae are higher compared with its incidence
in developed countries before massive vaccination. Therefore with massive vaccination
ofIranian young people « 20yr old), the costs of mumps infection and its
sequelae will decrease.