Volume 34, Issue 1 (2-2020)                   Med J Islam Repub Iran 2020 | Back to browse issues page

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Ghaffari H, Atashzar M R, Abdollahi H. Molecular imaging in tracking cancer stem cells: A review. Med J Islam Repub Iran 2020; 34 (1) :632-638
URL: http://mjiri.iums.ac.ir/article-1-6336-en.html
Molecular imaging in tracking cancer stem cells: A review
Hamed Ghaffari , Mohammad Reza Atashzar , Hamid Abdollahi
Department of Immunology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran , atashzar@sums.ac.ir
Abstract:   (1617 Views)
Cancer stem cells (CSCs) have critical roles in tumor development, progression, and recurrence. They are responsible for current cancer treatment failure and remain questionable for the design and development of new therapeutic strategies. With this issue, medical imaging provides several clues for finding biological mechanisms and strategies to treat CSCs. This review aims to summarize current molecular imaging approaches for detecting CSCs. In addition, some promising issues for CSCs finding and explaining biological mechanisms have been addressed. Among the molecular imaging approaches, modalities including Magnetic resonance imaging (MRI) and positron emission tomography (PET) have the greatest roles and several new approaches such as optical imaging are in progress.
Keywords: Cancer stem cells, Molecular imaging, MRI, PET, Optical imaging
Full-Text [PDF 1097 kb]   (560 Downloads)    
Type of Study: Review Article | Subject: Medical Physics and Radiation Therapy
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