From the Department of Cardiovascular Diseases and Kidney Transplantation, Golestan Hospital,Ahwaz University of Medical Sciences, Ahwaz, I.R. Iran. , h-adel@aums.ac.ir.h_adei41@hotmail.com.
Abstract: (4915 Views)
Recognition of the natural history and responsible leading factors for regression
of left ventricular hypertrophy after successful renal transplantation are very
important. The aim of this study was to assess the regression of left ventricular
hypertrophy after successful renal transplantation among uremic patients. In this
study 27 uremic patients (18 males and 9 females) with an average age of 38.5
years were randomly selected. Left ventricular mass index (LVMI) was calculated
before and after renal transplantation at the beginning, and at 4, 6 and 8 months.
The means of LVMI before and after transplantation were 180±19.3 g/m2
and 133.8±16.8 g/m2 respectively (p<0.00l ). The means of regression after transplantation
at 0,4,6 and 8 months of follow up were 1919/m2, 157.3 g/m2, 147.8 g/
m2 and 138.8 g/m2 respectively. There was a significant difference between the
means of hemoglobin concentration and blood pressure before and after transplantation
(p<0.00l). For instance the means of hemoglobin concentration and
blood pressure was 7.2±0.4 and 13.1±0.7 g/dL, 154±6 / 97±4.4, and 135±6.3/
89±3.8 mmHg respectively.
This study showed that maximum left ventricular hypertrophy regression
occurred 4 months after transplantation, then decreased to a minimum level of
147.8 and 135.8 g/m2 at 6 and 8 months after transplantation respectively. Restoration
of hemoglobin concentration and blood pressure to normal levels may be
recognized as a main cause of left ventricular hypertrophy regression.