From the Departments of Internal Medicine, Immunology and Physiology, Medical School, Tabriz University of Medical Sciences, Tabriz, l.R. Iran.
Abstract: (5054 Views)
Seroepidemiologic studies in developing countries show a high rate of
Helicobacter pylori (H. pylori) infections in children, in contrast to developed
countries. The aim of this study was to evaluate the prevalence of H. pylori in
children and teenagers in Tabriz, northwest of Iran.
In this prospective study 44 children and teenagers were randomly selected
to study serum IgG against H. pylori using ELISA method.
Our results indicated the presence of IgG in 83.5% of test subjects (83.7% in
females and 83.4% in males). In the 2-5 years age group 71.7% were IgG positive
and this percentage increased by age, i.e., 95.2% recorded as IgG positive in the
14-18 years age group (pO.05).
In general, our findings indicate that the prevalence of H. pylori in Tabriz,
like other developing countries is high from early age and increases further by
age. More studies are needed to clarify the reasons for this high prevalence.