From the Department of Radiation Oncology, Shiraz University of Medical Sciences, Shiraz, l.R. Iran
Abstract: (4397 Views)
In order to present the clinical features and outcome of patients with Ki-l
positive lymphoma and also the role of treatment modalities in this type of malignant
disease, twenty-six patients with peripheral lymphadenopathy and a biopsyproven
diagnosis ofKi-l positive lymphoma referring to the Radiation Oncology
Department during a seven year period were treated with chemotherapy and radiotherapy
according to the stage of the disease and after about 3 years of followup
the outcome was evaluated.
After an initial complete remission for a few months, most patients in advanced
stages and a few cases in early stages developed recurrence for whom
chemotherapy was started. The majority achieved remission again. After 3 years
of follow 'up 18 of 26 patients were alive with no evidence of disease.
As the behavior of this lymphoma is related to initial stage of disease rather
than to Ki-l expression, radiation therapy may be an acceptable modality adjunctive
to chemotherapy in patients with such lymphomas, particularly in those with
localized disease for getting better disease control.
Type of Study:
Original Research |
Subject:
Oncology