From the Department of Biochemistry, Government Medical College, Miraj, India, and the Dept. of Biology, Shahed University, Tehran, I.R. Iran.
Abstract: (4890 Views)
Hemodialysis is being implicated in the development of metabolic disturbances,
as complications have been observed and the role of trace metals in their
development has been questioned. In 78 renal failure patients who underwent
hemodialysis, serum levels of zinc and copper were determined before and after
first hemodialysis. Acute and chronic renal failure patients were found to have
lower serum zinc levels before hemodialysis and higher levels after hemodialysis,
while serum copper levels were found to be higher before hemodialysis and
to increase further after hemodialysis. Disturbances in acid-base balance lead to
acidosis which can alter the binding, transport and excretion of these elements.
Dialysis fluid containing salts of trace elements may have also contributed to this
alteration of trace element levels.