Medical Journal of The Islamic Republic of Iran (MJIRI)
Iran University of Medical Sciences
Wed, Jan 22, 2025
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Volume 38, Issue 1 (1-2024)
Med J Islam Repub Iran 2024 |
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Mirzaei M, Eshraghi A, Ghoddoosi M, Fatemi M, Eshraghi A, Azad Z, et al . Ovarian Angiosarcoma: A Case Report. Med J Islam Repub Iran 2024; 38 (1) :1197-1200
URL: http://mjiri.iums.ac.ir/article-1-8734-en.html
URL: http://mjiri.iums.ac.ir/article-1-8734-en.html
Monire Mirzaei 
, Abbas Eshraghi , Mahdiieh Ghoddoosi , Maedehalsadat Fatemi , Azhar Eshraghi , Zohreh Azad , Danial Fazilat-panah , Yavar Rajabzadeh
, Abbas Eshraghi , Mahdiieh Ghoddoosi , Maedehalsadat Fatemi , Azhar Eshraghi , Zohreh Azad , Danial Fazilat-panah , Yavar Rajabzadeh
Clinical Research Developmental Center, Qom University of Medical Sciences, Qom, Iran , aeshraqi@muq.ac.ir
Abstract: (82 Views)
Background: Sarcomas are one of the major groups of rare cancers and account for <1% of cancers worldwide. Ovarian angiosarcomas are rare and probably arise from carcinosarcomas, teratomas, or the rich ovarian vasculature. Here we present a case of ovarian angiosarcoma.
Case: A 35-year-old Iranian woman presented with a 6-month history of vague abdominal pain and a previous history of dermoid cyst. A pelvic MRI reported a large solid and cystic pelvic mass of ovarian origin. She underwent a left oophorectomy. The final pathologist's conclusion was malignant germ cell tumor including teratoma with malignant transformation in favor of transformation to angiosarcoma. The patient underwent total abdominal hysterectomy and right salpingo-oophorectomy and left salpingectomy. Surgical specimen revealed no malignancy including germ cell tumor, sarcoma or angiosarcoma
Conclusion: Dermoid cyst or mature cystic teratoma is the most common solid type tumor and the most common ovarian tumor occurring at a young age. Angiosarcomas of the ovary, like most other ovarian tumors, are discovered in late stages. There is no standard therapy for angiosarcoma of the ovary. In a review of previous cases, some have observed patients especially in the early stages while others have used adjuvant chemotherapy in the non-metastatic setting, basically doxorubicin-based.
Case: A 35-year-old Iranian woman presented with a 6-month history of vague abdominal pain and a previous history of dermoid cyst. A pelvic MRI reported a large solid and cystic pelvic mass of ovarian origin. She underwent a left oophorectomy. The final pathologist's conclusion was malignant germ cell tumor including teratoma with malignant transformation in favor of transformation to angiosarcoma. The patient underwent total abdominal hysterectomy and right salpingo-oophorectomy and left salpingectomy. Surgical specimen revealed no malignancy including germ cell tumor, sarcoma or angiosarcoma
Conclusion: Dermoid cyst or mature cystic teratoma is the most common solid type tumor and the most common ovarian tumor occurring at a young age. Angiosarcomas of the ovary, like most other ovarian tumors, are discovered in late stages. There is no standard therapy for angiosarcoma of the ovary. In a review of previous cases, some have observed patients especially in the early stages while others have used adjuvant chemotherapy in the non-metastatic setting, basically doxorubicin-based.
Type of Study: case report |
Subject:
Oncology
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