Volume 14, Issue 2 (8-2000)                   Med J Islam Repub Iran 2000 | Back to browse issues page

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TABARAIE B, SHARMA B, NEJATI M, AHMADI H, SHARMA P, GANGULY N K. COMPARATIVE CHARACTERIZATION OF PORINS FROM SALMONELLA TYPHIO-901 AND SALMONELLA TYPHIMURIUM RA-30. Med J Islam Repub Iran 2000; 14 (2) :161-168
URL: http://mjiri.iums.ac.ir/article-1-883-en.html
COMPARATIVE CHARACTERIZATION OF PORINS FROM SALMONELLA TYPHIO-901 AND SALMONELLA TYPHIMURIUM RA-30
BAHMAN TABARAIE , BALK SHARMA , MEHDI NEJATI , HOJAT AHMADI , PARVEEN SHARMA , NIRMAL K. GANGULY
From the Department of Bacterial Vaccines & Antigens, Production & Research Complex, Pasteur Institute of Iran, Tehran, I.R. Iran
Abstract:   (4174 Views)
Porins from Salmonella typhi 0-901 and Salmonella typhimurium Ra-30 were characterized and compared. The elution profile of porins from these salmonella species on Sepharose-48 and HPLC appear to be very similar. The findings were confirmed by the electrophoretic pattern which showed three types of porins, i.e. OmpC, OmpD and OmpF in both species. These porins appear to be similar, if not identical, as the LPS-absorbed antiporin antibodies reacted with homologous as well as heterologous antigens. The results of this study favour the use of porins as a common immunogen to control salmonellosis since porin patterns were found to be quite similar among the serotypes of salmonellae, unlike other enterobacterial species.
Keywords: Porins, S. typhi, S. typhimurium.
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Type of Study: Original Research: Basic Science in Medicine | Subject: Internal Medicine
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