Medical Journal of The Islamic Republic of Iran (MJIRI)
Iran University of Medical Sciences
Mon, Dec 30, 2024
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Volume 38, Issue 1 (1-2024)
Med J Islam Repub Iran 2024 |
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Seifollahi M, Heidarzadeh Arani M, Hoseini Shamsabadi R, Nakhaie S, Karimi Aghche M, Azadchehr M J et al . Serum Vitamin D and Zinc Levels in Children with Urinary Tract Infection without Confounding Factors: A Case-Control Study. Med J Islam Repub Iran 2024; 38 (1) :240-243
URL: http://mjiri.iums.ac.ir/article-1-8847-en.html
URL: http://mjiri.iums.ac.ir/article-1-8847-en.html
Mohsen Seifollahi 
, Marzieh Heidarzadeh Arani , Rozita Hoseini Shamsabadi , Shahrbanoo Nakhaie , Maesoumeh Karimi Aghche , Mohammad Javad Azadchehr , Amin Sadat Sharif
, Marzieh Heidarzadeh Arani , Rozita Hoseini Shamsabadi , Shahrbanoo Nakhaie , Maesoumeh Karimi Aghche , Mohammad Javad Azadchehr , Amin Sadat Sharif
Pediatric Nephrology Department, Hasheminejad Hospital, Iran University of Medical Sciences, Tehran, Iran , Sharif.a@iums.ac.ir
Abstract: (814 Views)
Background: Urinary tract infections (UTIs) are extremely prevalent bacterial infections among children. They have numerous potential causes. Without proper diagnosis and treatment, UTIs can lead to serious complications in children, including impaired growth, high blood pressure, protein in urine, and eventual chronic kidney disease. Zinc and vitamin D in sufficient concentrations help to maintain the health of the immune system. Therefore, their deficiency can cause various infections. Several factors can contribute to the development of UTIs. This article deals with the role of zinc and vitamin D as immune markers in UTI in children without other risk factors.
Methods: In this case-control study, serum zinc and vitamin D levels without any other risk factors were examined in 40 healthy children and 40 children with UTIs. Data analysis was done through SPSS 26 using the chi-square, the Fisher’s exact, and independent t tests.
Results: The study findings demonstrated a statistically significant distinction between the 2 groups regarding serum vitamin D and zinc levels (P < 0.001); 80% of children with UTIs and 17.5% in the healthy group had vitamin D deficiency. Also, 60% of the urinary infection group had zinc deficiency, whereas 17.5% of the healthy group had it.
Conclusion: Low serum zinc and vitamin D levels may increase susceptibility to pediatric UTI. Given the data, supplementation with zinc and vitamin D could play a significant role in treating active infections and preventing recurrence in susceptible children.
Methods: In this case-control study, serum zinc and vitamin D levels without any other risk factors were examined in 40 healthy children and 40 children with UTIs. Data analysis was done through SPSS 26 using the chi-square, the Fisher’s exact, and independent t tests.
Results: The study findings demonstrated a statistically significant distinction between the 2 groups regarding serum vitamin D and zinc levels (P < 0.001); 80% of children with UTIs and 17.5% in the healthy group had vitamin D deficiency. Also, 60% of the urinary infection group had zinc deficiency, whereas 17.5% of the healthy group had it.
Conclusion: Low serum zinc and vitamin D levels may increase susceptibility to pediatric UTI. Given the data, supplementation with zinc and vitamin D could play a significant role in treating active infections and preventing recurrence in susceptible children.
Type of Study: Original Research |
Subject:
Nephrology
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