From the Departments of Medicine and Pathology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran.
Abstract: (4707 Views)
156 Iranian patients with primary malignant tumors of the small intestine
were reviewed. Malignant lymphoma was the most common tumor type, comprising
128 patients (82%), followed by adenocarcinoma (22 patients, 14.1 %),
leiomyosarcoma (4 patients, 2.56%) and carcinoid tumor (2 patients, 1.28%).
Lymphomas and adenocarcinomas were primarily located in the duodenum
or jejunum, whereas leiomyosarcomas were more cornmon in the ileum. Abdominal
pain (73%), weight loss (68%), diarrhea (41% ), and nausea or vomiting (35%)
were the most common symptoms with these tumors.
Among the lymphoma group 95 patients (74.2%) had non-IPSID
(immunoproliferative small intestinal disease) lymphoma and 33 patients (25.8%)
had IPSID related lymphoma.
In contrast to the western world and far east countries in which malignant
small intestinal tumors are a disease of middle and old age groups and
adenocarcinoma is the most common tumor type, in our area, similar to some other
middle east and north African countries, lymphomas are much more frequent.
Although Iran is endemic for IPSID related lymphoma, the majority of these
tumors are non-IPSID lymphomas and appear in a very young age group (mean age
27 y).
Type of Study:
Original Research |
Subject:
Pathology