Volume 38, Issue 1 (1-2024)                   Med J Islam Repub Iran 2024 | Back to browse issues page

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Parviz S, Zeinalkhani F, Gity M, Saligheh Rad  H  , Fathi Kazerooni A, Nili F, et al . A Case of Primary Ovarian Primitive Neuroectodermal Tumor. Med J Islam Repub Iran 2024; 38 (1) :562-567
URL: http://mjiri.iums.ac.ir/article-1-9270-en.html
A Case of Primary Ovarian Primitive Neuroectodermal Tumor
Sara Parviz , Fahimeh Zeinalkhani , Masoumeh Gity , Hamidreza   Saligheh Rad  , Anahita Fathi Kazerooni , Fatemeh Nili , Peyman Kamali Hakim , Hadise Zeinalkhani
Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Tehran University of Medical Sciences, Tehran, Iran & Department of Radiology, Medical Imaging Center, Tehran University of Medical Sciences, Tehran, Iran , F_zeinalkhani@sina.tums.ac.ir
Abstract:   (56 Views)
Primitive neuroectodermal tumors (PNET) are a family of poorly differentiated malignant neoplasms of neuroectodermal origin. According to the location of origin, PNETs could be further categorized as central or peripheral. Peripheral PNET (pPNET) is an uncommon type that accounts for 1% of all soft tissue sarcomas and occurs outside the central and sympathetic nervous systems. Ovarian PNET is a very rare tumor with a high mortality rate. We report a case of pPNET originating from the pelvic cavity of a young woman. Ultrasound and Magnetic Resonance Imaging (MRI) findings demonstrated the presence of a high-grade malignant ovarian tumor. On microscopic evaluation, the tumor was composed of solid nests and sheets of small rounded cells, and on Immunohistochemical (IHC) evaluation, the tumor cells showed intense cell-membranous immunoactivity for MIC2 protein (CD99).
In the differential diagnosis of any invasive pelvic tumor in young women, pPNET should be considered.
 
Keywords: Primitive Neuroectodermal Tumor (PNET), Ovary, Magnetic Resonance Imaging (MRI) findings, Tumor, Diagnosis
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Type of Study: case report | Subject: Radiology
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