ZOLGHADRI J, GHADERI A, ALBORZI S, PARSANEZHAD M. SUCCESSFUL PREGNANCY OUTCOME WITH lUI IN PATIENTS WITH UNEXPLAINED RECURRENT MISCARRIAGE, WHOSE MALE PARTNERS HAVE LOW SCORE HYPO-OSMOTIC SWELLING TEST. Med J Islam Repub Iran 2003; 17 (2) :25-27
URL:
http://mjiri.iums.ac.ir/article-1-716-en.html
From the Department of Obstetrics & Gynecology Shiraz University of Medical Sciences, Shiraz, I.R.Iran. , JzoIghad@yahoo.com
Abstract: (7930 Views)
In order to determine outcome of pregnancy with lUI in patients with unexplained
recurrent miscarriage whose husbands have low hypo-osmotic swelling
test scores, a prospective clinical intervention was performed at a university referral
clinic of recurrent abortion.
Out of 56 patients whose husbands had abnormal hypo-osmotic swelling
tests, 43 patients underwent lUI, from which only 14 patients became pregnant
(treatment group) and 13 patients became spontaneously pregnant without lUI as
control group.
Our main outcome measure was successful pregnancy (continuation of pregnancy
after 20 weeks).
Among the 14 patients who became pregnant, 3 patients aborted below 20
weeks (21.4%), and 11 patients continued pregnancy after 20 weeks of gestation
(78.6%). In the control group among the 13 patients with spontaneous pregnancy,
8 patients aborted below 20 weeks (61.5%) and 5 patients continued pregnancy
over 20 weeks (36.4%), success rate ratio was 2.04% and the difference was statistically
significant (d= 4.49, p<0.05).
Treating the unexplained recurrent aborter whose male partner has a low
hypo-osmotic swelling test score with lUI could be effective. This is the first
study to present an ideal way for selection of recurrent aborters who benefit from
lUI. The probable mechanism for this effect may be selection of the best quality
sperms which will be discussed in detail.