From the Department of Pharmacology, Glasgow University, Glasgow, Scotland, U.K.
Abstract: (3761 Views)
Besides being a metabolite of nucleotides like ATP, adenosine is a mediator
of neuronal function in the central nervous system. Its actions are mediated by at
least three extracellular receptors. In this review different aspects of adenosine
such as biosynthesis, release, inactivation and its receptors are discussed. It also
covers pre- and postsynaptic effects as well as postreceptor mechanisms of
adenosine. Finally, therapeutic aspects of this neuromodulator have been discussed.
Type of Study:
Review Article |
Subject:
Pharmacology