Volume 9, Issue 4 (2-1996)                   Med J Islam Repub Iran 1996 | Back to browse issues page

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HOSSEINZADEH H, STONE T. ADENOSINE IN THE CENTRAL NERVOUS SYSTEM. Med J Islam Repub Iran 1996; 9 (4) :361-368
URL: http://mjiri.iums.ac.ir/article-1-1660-en.html
ADENOSINE IN THE CENTRAL NERVOUS SYSTEM
H HOSSEINZADEH , T.W STONE
From the Department of Pharmacology, Glasgow University, Glasgow, Scotland, U.K.
Abstract:   (3850 Views)
Besides being a metabolite of nucleotides like ATP, adenosine is a mediator of neuronal function in the central nervous system. Its actions are mediated by at least three extracellular receptors. In this review different aspects of adenosine such as biosynthesis, release, inactivation and its receptors are discussed. It also covers pre- and postsynaptic effects as well as postreceptor mechanisms of adenosine. Finally, therapeutic aspects of this neuromodulator have been discussed.
Keywords: Adenosine, Purine, Central nervous system, Review.
Full-Text [PDF 599 kb]   (2291 Downloads)    
Type of Study: Review Article | Subject: Pharmacology
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