Volume 17, Issue 3 (11-2003)                   Med J Islam Repub Iran 2003 | Back to browse issues page

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MARDANI M, KESHTKAR JAHROMI M, HOLAKOI NAINI K, ZINALI M. THE EFFICACY OF ORAL RIBAVIRIN IN THE TREATMENT OF 81 PROVED CASES OF CRIMEAN-CONGO HEMORRHAGIC FEVER (CCHF) IN IRAN (1999-2001). Med J Islam Repub Iran 2003; 17 (3) :193-195
URL: http://mjiri.iums.ac.ir/article-1-680-en.html
THE EFFICACY OF ORAL RIBAVIRIN IN THE TREATMENT OF 81 PROVED CASES OF CRIMEAN-CONGO HEMORRHAGIC FEVER (CCHF) IN IRAN (1999-2001)
M MARDANI , M KESHTKAR JAHROMI , K HOLAKOI NAINI , M ZINALI
From the Dept. of Infectious Diseases and Tropical Medicine, Shaheed Beheshti University of Medical Sciences, and the Dept. of Epidemiology, Tehran University of Medical Sciences, Tehran, Iran. , mmardani@sbmu.ac.ir
Abstract:   (5108 Views)
Crimean-Congo Hemorrhagic Fever is a fatal viral disease that occurs in some parts of Africa, Asia, Eastern Europe and the Middle-East. Primarily it is a zoonosis but can be seen sporadically in humans. Recently outbreaks have been reported from Pakistan, Afghanistan, Saudi Arabia, United Arab Emirates and Iran. In this retrospective study, we evaluated the efficacy of oral Ribavirin in the treatment of CCHF cases, by comparing the outcome in two groups of treated and non-treated confirmed CCHF cases. 81 confirmed CCHF cases (by serology or viral culture) were evaluated for the incidence of outcome (death or recovery ) in the form of an analytic case-control study. 61 out of 69 treated cases and 5 out of 12 non-treated cases survived. Oral Ribavirin with an efficacy of 91 % can be an effective medical therapy for management of Crimean Congo Hemorrhagic Fever.
Keywords: Congo Hemorrhagic Fever, Oral Ribavirin, Efficacy.
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Type of Study: Original Research | Subject: Infectious Disease
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